Astrocytes rescue neuronal health after cisplatin treatment through mitochondrial transfer
Abstract Neurodegenerative disorders, including chemotherapy-induced cognitive impairment, are associated with neuronal mitochondrial dysfunction.Cisplatin, a commonly used chemotherapeutic, induces neuronal mitochondrial dysfunction in vivo and in vitro.Astrocytes are key players in supporting neuronal development, synaptogenesis, axonal growth, m